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The ocean plays a crucial role in regulating climate patterns and influencing weather conditions and extreme events. Changes in the ocean state have profound impacts on ocean-based industries such as fisheries, aquaculture, marine renewable energies, and maritime transportation. There is no doubt that preserving the marine environment is essential to oceanic biodiversity and the overall health of the planet. To achieve climate adaptation, carbon management, and marine resource conservation, it is urgently needed to better understand and monitor the physical, biogeochemical (BGC), and ecosystem dynamics of the ocean, and document the interplay of these processes. For the past 25 years, the Argo float array has provided real-time, freely accessible global temperature and salinity data in the upper 2,000 meters of the ocean. Argo has enabled important breakthroughs in ocean science, yielding over 6,000 research papers. New Argo design, OneArgo, was presented at the OceanObs19 conference held in 2019. The expansion of Argo to OneArgo will integrate BGC parameters in the upper 2,000 m (BGC Argo), extend profiling depth beyond 2,000 m to the ocean bottom (Deep Argo), and stretch coverage to the rapidly changing polar regions (Polar Argo). OneArgo will be instrumental for improving monitoring of oceanic changes in unprecedented ways, enabling increased understanding and forecasting of ocean impacts on weather and long-term climate variability. Simultaneously, OneArgo will enhance synergies with other components of the global ocean observing system, including satellites, ships, moorings, gliders, etc., complementing each other. This session will share the latest scientific breakthroughs utilizing OneArgo data, and describe the ability of OneArgo to transform the global ocean observing system.